Pyridine indole hybrids as novel potent CYP17A1 inhibitors
Pyridine indole hybrids as novel potent CYP17A1 inhibitors
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Publisher
England: Taylor & Francis
Journal title
Language
English
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Publisher
England: Taylor & Francis
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Contents
Prostate cancer (PCa) is one of the most prevalent malignancies affecting men worldwide, and androgen deprivation therapy (ADT) is a primary treatment approach. CYP17A1 inhibitors like abiraterone target the steroidogenic pathway to reduce androgen levels, but their clinical efficacy is limited by drug resistance and adverse effects. This study rep...
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Full title
Pyridine indole hybrids as novel potent CYP17A1 inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_2b0f63253cc24dfc970b0890757145a1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b0f63253cc24dfc970b0890757145a1
Other Identifiers
ISSN
1475-6374,1475-6366
E-ISSN
1475-6374
DOI
10.1080/14756366.2025.2463014
