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23 results for Wróbel,+Tomasz+M

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Allosteric Modulators of Dopamine D2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis
Author / Creator:Kaczor, Agnieszka A. ; Wróbel, Tomasz M. ; Bartuzi, Damian
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-01, Vol.28 (1), p.178
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Methods of Lysergic Acid Synthesis-The Key Ergot Alkaloid
Author / Creator:Jastrzębski, Michał K ; Kaczor, Agnieszka A ; Wróbel, Tomasz M
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-10, Vol.27 (21), p.7322
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Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D2 Receptor Ligand
Author / Creator:Kondej, Magda ; Bartyzel, Agata ; Pitucha, Monika ; Wróbel, Tomasz M. ; Silva, Andrea G. ; Matosiuk, Dariusz ; Castro, Marián ; Kaczor, Agnieszka A.
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-09, Vol.23 (9), p.2249
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Allosteric Modulators of Dopamine D 2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis
Author / Creator:Kaczor, Agnieszka A ; Wróbel, Tomasz M ; Bartuzi, Damian
Publisher:Switzerland
Journal title:Molecules (Basel, Switzerland), 2023, Vol.28 (1)
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Pyridine indole hybrids as novel potent CYP17A1 inhibitors
Author / Creator:Wróbel, Tomasz M ; Grudzińska, Angelika ; Yakubu, Jibira ; du Toit, Therina ; Sharma, Katyayani ; Harrington, Jeremiah C ; Björkling, Fredrik ; Jørgensen, Flemming Steen ; Pandey, Amit V
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2025-12, Vol.40 (1), p.2463014
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Experimental and Computational Structural Studies of 2,3,5-Trisubstituted and 1,2,3,5-Tetrasubstituted Indoles as Non-Competitive Antagonists of GluK1/GluK2 Receptors
Author / Creator:Bartyzel, Agata ; Kaczor, Agnieszka A ; Mahmoudi, Ghodrat ; Masoudiasl, Ardavan ; Wróbel, Tomasz M ; Pitucha, Monika ; Matosiuk, Dariusz
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-04, Vol.27 (8), p.2479
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Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT1A and 5-HT2A Receptor Ligands
Author / Creator:Kaczor, Agnieszka A. ; Kędzierska, Ewa ; Wróbel, Tomasz M. ; Grudzińska, Angelika ; Pawlak, Angelika ; Laitinen, Tuomo ; Bartyzel, Agata
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-01, Vol.28 (1), p.383
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Thermal and spectroscopic studies of 2,3,5-trisubstituted and 1,2,3,5-tetrasubstituted indoles as non-competitive antagonists of GluK1/GluK2 receptors
Author / Creator:Bartyzel, Agata ; Kaczor, Agnieszka A. ; Głuchowska, Halina ; Pitucha, Monika ; Wróbel, Tomasz M. ; Matosiuk, Dariusz
Publisher:Cham: Springer International Publishing
Journal title:Journal of thermal analysis and calorimetry, 2018-08, Vol.133 (2), p.935-944
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Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia
Author / Creator:Stępnicki, Piotr ; Wośko, Sylwia ; Bartyzel, Agata ; Zięba, Agata ; Bartuzi, Damian ; Szałaj, Klaudia ; Wróbel, Tomasz M. ; Fornal, Emilia ; Carlsson, Jens ; Kędzierska, Ewa ; Poleszak, Ewa ; Castro, Marián ; Kaczor, Agnieszka A.
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-05, Vol.28 (10), p.4211
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Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes
Author / Creator:Bartuzi, Damian ; Kędzierska, Ewa ; Targowska-Duda, Katarzyna M. ; Koszła, Oliwia ; Wróbel, Tomasz M. ; Jademyr, Simon ; Karcz, Tadeusz ; Szczepańska, Katarzyna ; Stępnicki, Piotr ; Wronikowska-Denysiuk, Olga ; Biała, Grażyna ; Handzlik, Jadwiga ; Kristensen, Jesper L. ; Poso, Antti ; Kaczor, Agnieszka A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-12, Vol.12 (1), p.21192-14, Article 21192
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Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation
Author / Creator:Stępnicki, Piotr ; Wronikowska-Denysiuk, Olga ; Zięba, Agata ; Targowska-Duda, Katarzyna M. ; Bartyzel, Agata ; Wróbel, Martyna Z. ; Wróbel, Tomasz M. ; Szałaj, Klaudia ; Chodkowski, Andrzej ; Mirecka, Karolina ; Budzyńska, Barbara ; Fornal, Emilia ; Turło, Jadwiga ; Castro, Marián ; Kaczor, Agnieszka A.
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2209828-2209828
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Synthesis and Structure-Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents
Author / Creator:Wróbel, Tomasz M ; Rogova, Oksana ; Sharma, Katyayani ; Rojas Velazquez, Maria Natalia ; Pandey, Amit V ; Jørgensen, Flemming Steen ; Arendrup, Frederic S ; Andersen, Kasper L ; Björkling, Fredrik
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2022-01, Vol.12 (2), p.165
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Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents
Author / Creator:Wróbel, Tomasz M ; Rogova, Oksana ; Andersen, Kasper L ; Yadav, Rahul ; Brixius-Anderko, Simone ; Scott, Emily E ; Olsen, Lars ; Jørgensen, Flemming Steen ; Björkling, Fredrik
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-07, Vol.21 (14), p.4868
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Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity
Author / Creator:Wróbel, Tomasz M ; Kosikowska, Urszula ; Kaczor, Agnieszka A ; Andrzejczuk, Sylwia ; Karczmarzyk, Zbigniew ; Wysocki, Waldemar ; Urbańczyk-Lipkowska, Zofia ; Morawiak, Maja ; Matosiuk, Dariusz
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2015-08, Vol.20 (8), p.14761-14776
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The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases
Author / Creator:Koszła, Oliwia ; Sołek, Przemysław ; Woźniak, Sylwia ; Kędzierska, Ewa ; Wróbel, Tomasz M ; Kondej, Magda ; Archała, Aneta ; Stępnicki, Piotr ; Biała, Grażyna ; Matosiuk, Dariusz ; Kaczor, Agnieszka A
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-11, Vol.21 (22), p.8849
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Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis
Author / Creator:Wróbel, Tomasz M ; Sharma, Katyayani ; Mannella, Iole ; Oliaro-Bosso, Simonetta ; Nieckarz, Patrycja ; Du Toit, Therina ; Voegel, Clarissa Daniela ; Rojas Velazquez, Maria Natalia ; Yakubu, Jibira ; Matveeva, Anna ; Therkelsen, Søren ; Jørgensen, Flemming Steen ; Pandey, Amit V ; Pippione, Agnese C ; Lolli, Marco L ; Boschi, Donatella ; Björkling, Fredrik
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-09, Vol.13 (9), p.1349
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Development and Characterization of Novel Selective, Non-Basic Dopamine D 2 Receptor Antagonists for the Treatment of Schizophrenia
Author / Creator:Stępnicki, Piotr ; Wośko, Sylwia ; Bartyzel, Agata ; Zięba, Agata ; Bartuzi, Damian ; Szałaj, Klaudia ; Wróbel, Tomasz M ; Fornal, Emilia ; Carlsson, Jens ; Kędzierska, Ewa ; Poleszak, Ewa ; Castro, Marián ; Kaczor, Agnieszka A
Publisher:Switzerland
Journal title:Molecules (Basel, Switzerland), 2023-05, Vol.28 (10)
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Allosteric Modulators of Dopamine D[sub.2] Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis
Author / Creator:Kaczor, Agnieszka A ; Wróbel, Tomasz M ; Bartuzi, Damian
Publisher:MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-12, Vol.28 (1)
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Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT[sub.1A] and 5-HT[sub.2A] Receptor Ligands
Author / Creator:Kaczor, Agnieszka A ; Kędzierska, Ewa ; Wróbel, Tomasz M ; Grudzińska, Angelika ; Pawlak, Angelika ; Laitinen, Tuomo ; Bartyzel, Agata
Publisher:MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-01, Vol.28 (1)
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ArticlesPeer ReviewedFull Text
Development and Characterization of Novel Selective, Non-Basic Dopamine D[sub.2] Receptor Antagonists for the Treatment of Schizophrenia
Author / Creator:Stępnicki, Piotr ; Wośko, Sylwia ; Bartyzel, Agata ; Zięba, Agata ; Bartuzi, Damian ; Szałaj, Klaudia ; Wróbel, Tomasz M ; Fornal, Emilia ; Carlsson, Jens ; Kędzierska, Ewa ; Poleszak, Ewa ; Castro, Marián ; Kaczor, Agnieszka A
Publisher:MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-05, Vol.28 (10)
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Showing 1 to 20 of 23 results

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Allosteric Modulators of Dopamine D2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis

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Methods of Lysergic Acid Synthesis-The Key Ergot Alkaloid

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Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D2 Receptor Ligand

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Allosteric Modulators of Dopamine D 2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis

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Pyridine indole hybrids as novel potent CYP17A1 inhibitors

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Experimental and Computational Structural Studies of 2,3,5-Trisubstituted and 1,2,3,5-Tetrasubstituted Indoles as Non-Competitive Antagonists of GluK1/GluK2 Receptors

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Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT1A and 5-HT2A Receptor Ligands

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Thermal and spectroscopic studies of 2,3,5-trisubstituted and 1,2,3,5-tetrasubstituted indoles as non-competitive antagonists of GluK1/GluK2 receptors

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Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia

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Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes

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Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation

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Synthesis and Structure-Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents

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Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents

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Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity

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The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases

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Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis

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Development and Characterization of Novel Selective, Non-Basic Dopamine D 2 Receptor Antagonists for the Treatment of Schizophrenia

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Allosteric Modulators of Dopamine D[sub.2] Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis

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Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT[sub.1A] and 5-HT[sub.2A] Receptor Ligands

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Development and Characterization of Novel Selective, Non-Basic Dopamine D[sub.2] Receptor Antagonists for the Treatment of Schizophrenia

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