Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The protein toxin C3bot from
is a mono-ADP-ribosyltransferase that selectively intoxicates monocyte-derived cells such as macrophages, osteoclasts, and dendritic cells (DCs) by cytosolic modification of Rho-A, -B, and -C. Here, we investigated the application of C3bot as well as its non-toxic variant C3bot
as transporters for selective delive...
Alternative Titles
Full title
Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2b66a39aac1e4a8d92a5e296924ca4d8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b66a39aac1e4a8d92a5e296924ca4d8
Other Identifiers
ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins14100711
