How structural elements evolving from bacterial to human SLC6 transporters enabled new functional pr...
How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Much of the structure-based mechanistic understandings of the function of SLC6A neurotransmitter transporters emerged from the study of their bacterial LeuT-fold homologs. It has become evident, however, that structural differences such as the long N- and C-termini of the eukaryotic neurotransmitter transporters are involved in an expanded set of f...
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How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties
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TN_cdi_doaj_primary_oai_doaj_org_article_2b821b56ccad4ee3b09d3e0c2f9e8f8d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b821b56ccad4ee3b09d3e0c2f9e8f8d
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ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-018-0495-6