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How structural elements evolving from bacterial to human SLC6 transporters enabled new functional pr...

How structural elements evolving from bacterial to human SLC6 transporters enabled new functional pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b821b56ccad4ee3b09d3e0c2f9e8f8d

How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties

About this item

Full title

How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties

Publisher

England: BioMed Central Ltd

Journal title

BMC biology, 2018-03, Vol.16 (1), p.31-31, Article 31

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Much of the structure-based mechanistic understandings of the function of SLC6A neurotransmitter transporters emerged from the study of their bacterial LeuT-fold homologs. It has become evident, however, that structural differences such as the long N- and C-termini of the eukaryotic neurotransmitter transporters are involved in an expanded set of f...

Alternative Titles

Full title

How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2b821b56ccad4ee3b09d3e0c2f9e8f8d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b821b56ccad4ee3b09d3e0c2f9e8f8d

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-018-0495-6

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