Widespread intronic polyadenylation diversifies immune cell transcriptomes
Widespread intronic polyadenylation diversifies immune cell transcriptomes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Alternative cleavage and polyadenylation (ApA) is known to alter untranslated region (3ʹUTR) length but can also recognize intronic polyadenylation (IpA) signals to generate transcripts that lose part or all of the coding region. We analyzed 46 3ʹ-seq and RNA-seq profiles from normal human tissues, primary immune cells, and multiple myeloma (MM) sa...
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Widespread intronic polyadenylation diversifies immune cell transcriptomes
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TN_cdi_doaj_primary_oai_doaj_org_article_2bbdcae153214b559f2c223b91762442
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2bbdcae153214b559f2c223b91762442
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04112-z