Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference
Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Multiplexed single-cell RNA-seq analysis of multiple samples using pooling is a promising experimental design, offering increased throughput while allowing to overcome batch variation. To reconstruct the sample identify of each cell, genetic variants that segregate between the samples in the pool have been proposed as natural barcode for cell demul...
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Full title
Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference
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TN_cdi_doaj_primary_oai_doaj_org_article_2c2f9e81b8754d808ede35ffc89ef577
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c2f9e81b8754d808ede35ffc89ef577
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-019-1865-2
