Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Clinical trials where cancer patients were treated with protease inhibitors have suggested that the serine protease, prostasin, may act as a tumour suppressor. Prostasin is proteolytically activated by the serine protease, matriptase, which has a very high oncogenic potential. Prostasin is inhibited by protease nexin-1 (PN-1) and the two isoforms e...
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Full title
Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_2c6dc1eb6f7c4e138c8b39d8d33faf7b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c6dc1eb6f7c4e138c8b39d8d33faf7b
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-9-201
