Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples
Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Poly (ADP-ribose) (PAR) is a negatively charged polymer that is biosynthesized by Poly (ADP-ribose) Polymerase-1 (PARP-1) and regulates various cellular processes. Alpha-synuclein (αSyn) is an intrinsically disordered protein (IDP) that has been directly implicated with driving the onset and progression of Parkinson's disease (PD). The mechanisms b...
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Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples
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TN_cdi_doaj_primary_oai_doaj_org_article_2deab56410f34193b971dfcf9ccf783e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2deab56410f34193b971dfcf9ccf783e
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2021.704041
