Ruthenium(II)-enabled para-selective C–H difluoromethylation of anilides and their derivatives
Ruthenium(II)-enabled para-selective C–H difluoromethylation of anilides and their derivatives
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Transition-metal-catalyzed direct site-selective functionalization of arene C–H bonds has emerged as an innovative approach for building the core structure of pharmaceutical agents and other versatile complex compounds. However,
para
-selective C–H functionalization has seldom been explored, only a few examples, such as steric-hindered arenes...
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Ruthenium(II)-enabled para-selective C–H difluoromethylation of anilides and their derivatives
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TN_cdi_doaj_primary_oai_doaj_org_article_2e010d01252e4fb4a3b57e589263ff4a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e010d01252e4fb4a3b57e589263ff4a
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03341-6