Conformational Essentials Responsible for Neurotoxicity of Aβ42 Aggregates Revealed by Antibodies ag...
Conformational Essentials Responsible for Neurotoxicity of Aβ42 Aggregates Revealed by Antibodies against Oligomeric Aβ42
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Basel: MDPI AG
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English
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Basel: MDPI AG
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Soluble aggregation of amyloid β-peptide 1-42 (Aβ42) and deposition of Aβ42 aggregates are the initial pathological hallmarks of Alzheimer’s disease (AD). The bipolar nature of Aβ42 molecule results in its ability to assemble into distinct oligomers and higher aggregates, which may drive some of the phenotypic heterogeneity observed in AD. Agents t...
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Conformational Essentials Responsible for Neurotoxicity of Aβ42 Aggregates Revealed by Antibodies against Oligomeric Aβ42
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TN_cdi_doaj_primary_oai_doaj_org_article_2e1be1aaf0c64670a9db195c7ed1525b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e1be1aaf0c64670a9db195c7ed1525b
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27196751
