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MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination v...

MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination v...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e4ad845f0d84b08a749e3c99ffb08a1

MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-κB Signaling Pathway

About this item

Full title

MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-κB Signaling Pathway

Publisher

New Zealand: Taylor & Francis Ltd

Journal title

Drug design, development and therapy, 2020-01, Vol.14, p.1377-1389

Language

English

Formats

Publication information

Publisher

New Zealand: Taylor & Francis Ltd

More information

Scope and Contents

Contents

Demyelination causes neurological deficits involving visual, motor, sensory symptoms. Deregulation of several enzymes has been identified in demyelination, which holds potential for the development of treatment strategies for demyelination. However, the specific effect of methionine sulfoxide reductase A (MsrA) on demyelination remains unclear. Hen...

Alternative Titles

Full title

MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-κB Signaling Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2e4ad845f0d84b08a749e3c99ffb08a1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e4ad845f0d84b08a749e3c99ffb08a1

Other Identifiers

ISSN

1177-8881

E-ISSN

1177-8881

DOI

10.2147/DDDT.S223218

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