Gating mechanism of hyperpolarization-activated HCN pacemaker channels
Gating mechanism of hyperpolarization-activated HCN pacemaker channels
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are essential for rhythmic activity in the heart and brain, and mutations in HCN channels are linked to heart arrhythmia and epilepsy. HCN channels belong to the family of voltage-gated K
+
(Kv) channels. However, why HCN channels are activated by hyperpolarization whereas Kv...
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Full title
Gating mechanism of hyperpolarization-activated HCN pacemaker channels
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TN_cdi_doaj_primary_oai_doaj_org_article_2e930f15eab946698c97b37cf9434cbf
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e930f15eab946698c97b37cf9434cbf
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15233-9
