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RNA editing derived epitopes function as cancer antigens to elicit immune responses

RNA editing derived epitopes function as cancer antigens to elicit immune responses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e9bfb402d00408685976df0bcbc9b99

RNA editing derived epitopes function as cancer antigens to elicit immune responses

About this item

Full title

RNA editing derived epitopes function as cancer antigens to elicit immune responses

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-09, Vol.9 (1), p.3919-10, Article 3919

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In addition to genomic mutations, RNA editing is another major mechanism creating sequence variations in proteins by introducing nucleotide changes in mRNA sequences. Deregulated RNA editing contributes to different types of human diseases, including cancers. Here we report that peptides generated as a consequence of RNA editing are indeed naturall...

Alternative Titles

Full title

RNA editing derived epitopes function as cancer antigens to elicit immune responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2e9bfb402d00408685976df0bcbc9b99

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e9bfb402d00408685976df0bcbc9b99

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-06405-9

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