Design, Synthesis, Molecular Docking, and Biological Evaluation of Pyrazole Hybrid Chalcone Conjugat...
Design, Synthesis, Molecular Docking, and Biological Evaluation of Pyrazole Hybrid Chalcone Conjugates as Potential Anticancer Agents and Tubulin Polymerization Inhibitors
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Some (
)-3-(3-(4-(benzyloxy)phenyl)-1-phenyl-1
-pyrazol-4-yl)-1-phenylprop-2-en-1-one conjugates
-
were designed; synthesized; characterized by
H,
C NMR, and ESI-MS; and evaluated for tubulin polymerization inhibitory activity and in vitro cytotoxicity against breast (MCF-7), cervical (SiHa), and prostate (PC-3) cancer cell lines,...
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Full title
Design, Synthesis, Molecular Docking, and Biological Evaluation of Pyrazole Hybrid Chalcone Conjugates as Potential Anticancer Agents and Tubulin Polymerization Inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_2f2a169b12e640f0a659a9341b0d9fdc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f2a169b12e640f0a659a9341b0d9fdc
Other Identifiers
ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph15030280
