Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced...
Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced intervertebral disc degeneration
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Author / Creator
Lai, Hehuan , Fan, Jialin , Zhang, Yejin , Pan, Bin , Pan, Wenzheng , Fang, Jiawei , Ni, Kainan , Chen, Zhenzhong , Liu, Shijie , Lou, Chao and He, Dengwei
Publisher
Iran: Mashhad University of Medical Sciences
Journal title
Language
English
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Publication information
Publisher
Iran: Mashhad University of Medical Sciences
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Scope and Contents
Contents
Recently, studies on microRNAs (miRNAs) and their targets and related genes have provided new therapeutic opportunities for controlling intervertebral disc degeneration (IDD). We aimed to investigate the effects of miR-148a-3p overexpression on IDD progression.
This study used microRNA microarrays to analyze key regulators of IDD. Q-PCR was used...
Alternative Titles
Full title
Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced intervertebral disc degeneration
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2f69423e4b234b13bdf8190822bd2d64
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f69423e4b234b13bdf8190822bd2d64
Other Identifiers
ISSN
2008-3866
E-ISSN
2008-3874
DOI
10.22038/IJBMS.2022.64645.14228
