The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein...
The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models
About this item
Full title
Author / Creator
Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: The Company of Biologists Ltd
Subjects
More information
Scope and Contents
Contents
Heterozygous mutations in the GBA1 gene - encoding lysosomal glucocerebrosidase (GCase) - are the most common genetic risk factors for Parkinson's disease (PD). Experimental evidence suggests a correlation between decreased GCase activity and accumulation of alpha-synuclein (aSyn). To enable a better understanding of the relationship between aSyn a...
Alternative Titles
Full title
The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2ff4a4f7438a460f8a91ec3fc7c58bc4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ff4a4f7438a460f8a91ec3fc7c58bc4
Other Identifiers
ISSN
1754-8403,1754-8411
E-ISSN
1754-8411
DOI
10.1242/dmm.049192
