TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial...
TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells
About this item
Full title
Author / Creator
Alpizar, Yeranddy A. , Boonen, Brett , Sanchez, Alicia , Jung, Carole , López-Requena, Alejandro , Naert, Robbe , Steelant, Brecht , Luyts, Katrien , Plata, Cristina , De Vooght, Vanessa , Vanoirbeek, Jeroen A. J. , Meseguer, Victor M. , Voets, Thomas , Alvarez, Julio L. , Hellings, Peter W. , Hoet, Peter H. M. , Nemery, Benoit , Valverde, Miguel A. and Talavera, Karel
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Lipopolysaccharides (LPS), the major components of the wall of gram-negative bacteria, trigger powerful defensive responses in the airways via mechanisms thought to rely solely on the Toll-like receptor 4 (TLR4) immune pathway. Here we show that airway epithelial cells display an increase in intracellular Ca
2+
concentration within seconds of...
Alternative Titles
Full title
TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells
Authors, Artists and Contributors
Author / Creator
Boonen, Brett
Sanchez, Alicia
Jung, Carole
López-Requena, Alejandro
Naert, Robbe
Steelant, Brecht
Luyts, Katrien
Plata, Cristina
De Vooght, Vanessa
Vanoirbeek, Jeroen A. J.
Meseguer, Victor M.
Voets, Thomas
Alvarez, Julio L.
Hellings, Peter W.
Hoet, Peter H. M.
Nemery, Benoit
Valverde, Miguel A.
Talavera, Karel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_305c11c87f63412e9d5471df82642beb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_305c11c87f63412e9d5471df82642beb
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01201-3
