Progranulin regulates neuronal outgrowth independent of sortilin
Progranulin regulates neuronal outgrowth independent of sortilin
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Progranulin (PGRN), a widely secreted growth factor, is involved in multiple biological functions, and mutations located within the PGRN gene (GRN) are a major cause of frontotemporal lobar degeneration with TDP-43-positive inclusions (FLTD-TDP). In light of recent reports suggesting PGRN functions as a protective neurotrophic factor and that sorti...
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Full title
Progranulin regulates neuronal outgrowth independent of sortilin
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TN_cdi_doaj_primary_oai_doaj_org_article_312a8fea8e8b42d0acd80a25669f99cb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_312a8fea8e8b42d0acd80a25669f99cb
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-7-33
