Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation
Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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We previously showed that NUDT21-spanning copy-number variations (CNVs) are associated with intellectual disability (Gennarino et al., 2015). However, the patients’ CNVs also included other genes. To determine if reduced NUDT21 function alone can cause disease, we generated Nudt21+/- mice to mimic NUDT21-deletion patients. We found that although th...
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Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation
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TN_cdi_doaj_primary_oai_doaj_org_article_31585665f6474631989096c543a84a1e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_31585665f6474631989096c543a84a1e
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2050-084X
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2050-084X
DOI
10.7554/eLife.50895