T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiv...
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses
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Author / Creator
Ogbe, Ane , Kronsteiner, Barbara , Skelly, Donal T. , Pace, Matthew , Brown, Anthony , Adland, Emily , Adair, Kareena , Akhter, Hossain Delowar , Ali, Mohammad , Ali, Serat-E , Angyal, Adrienn , Ansari, M. Azim , Arancibia-Cárcamo, Carolina V. , Brown, Helen , Chinnakannan, Senthil , Conlon, Christopher , de Lara, Catherine , de Silva, Thushan , Dold, Christina , Dong, Tao , Donnison, Timothy , Eyre, David , Flaxman, Amy , Fletcher, Helen , Gardner, Joshua , Grist, James T. , Hackstein, Carl-Philipp , Jaruthamsophon, Kanoot , Jeffery, Katie , Lambe, Teresa , Lee, Lian , Li, Wenqin , Lim, Nicholas , Matthews, Philippa C. , Mentzer, Alexander J. , Moore, Shona C. , Naisbitt, Dean J. , Ogese, Monday , Ogg, Graham , Openshaw, Peter , Pirmohamed, Munir , Pollard, Andrew J. , Ramamurthy, Narayan , Rongkard, Patpong , Rowland-Jones, Sarah , Sampson, Oliver , Screaton, Gavin , Sette, Alessandro , Stafford, Lizzie , Thompson, Craig , Thomson, Paul J. , Thwaites, Ryan , Vieira, Vinicius , Weiskopf, Daniela , Zacharopoulou, Panagiota , Turtle, Lance , Klenerman, Paul , Goulder, Philip , Frater, John , Barnes, Eleanor , Dunachie, Susanna , Oxford Immunology Network Covid-19 Response T Cell Consortium and Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Identification of protective T cell responses against SARS-CoV-2 requires distinguishing people infected with SARS-CoV-2 from those with cross-reactive immunity to other coronaviruses. Here we show a range of T cell assays that differentially capture immune function to characterise SARS-CoV-2 responses. Strong ex vivo ELISpot and proliferation resp...
Alternative Titles
Full title
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses
Authors, Artists and Contributors
Author / Creator
Kronsteiner, Barbara
Skelly, Donal T.
Pace, Matthew
Brown, Anthony
Adland, Emily
Adair, Kareena
Akhter, Hossain Delowar
Ali, Mohammad
Ali, Serat-E
Angyal, Adrienn
Ansari, M. Azim
Arancibia-Cárcamo, Carolina V.
Brown, Helen
Chinnakannan, Senthil
Conlon, Christopher
de Lara, Catherine
de Silva, Thushan
Dold, Christina
Dong, Tao
Donnison, Timothy
Eyre, David
Flaxman, Amy
Fletcher, Helen
Gardner, Joshua
Grist, James T.
Hackstein, Carl-Philipp
Jaruthamsophon, Kanoot
Jeffery, Katie
Lambe, Teresa
Lee, Lian
Li, Wenqin
Lim, Nicholas
Matthews, Philippa C.
Mentzer, Alexander J.
Moore, Shona C.
Naisbitt, Dean J.
Ogese, Monday
Ogg, Graham
Openshaw, Peter
Pirmohamed, Munir
Pollard, Andrew J.
Ramamurthy, Narayan
Rongkard, Patpong
Rowland-Jones, Sarah
Sampson, Oliver
Screaton, Gavin
Sette, Alessandro
Stafford, Lizzie
Thompson, Craig
Thomson, Paul J.
Thwaites, Ryan
Vieira, Vinicius
Weiskopf, Daniela
Zacharopoulou, Panagiota
Turtle, Lance
Klenerman, Paul
Goulder, Philip
Frater, John
Barnes, Eleanor
Dunachie, Susanna
Oxford Immunology Network Covid-19 Response T Cell Consortium
Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_316bcccee68f41c8b075256474e98d3e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_316bcccee68f41c8b075256474e98d3e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21856-3
