The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity
The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Overexpression or mutation of α-Synuclein is associated with protein aggregation and interferes with a number of cellular processes, including mitochondrial integrity and function. We used a whole-genome screen in the fruit fly Drosophila melanogaster to search for novel genetic modifiers of human [A53T]α-Synuclein-induced neurotoxicity. Decreased...
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The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity
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TN_cdi_doaj_primary_oai_doaj_org_article_321fc408e4734e928e51d7b354c0b140
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_321fc408e4734e928e51d7b354c0b140
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002488
