Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP tre...
Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP treatment
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Author / Creator
Du, Jing , Chen, Weiwei , Yang, Lijuan , Dai, Juanjuan , Guo, Jiwei , Wu, Yan , Gong, Kaikai , Zhang, Jian , Yu, Ning , Xie, Zhen and Xi, Sichuan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Deregulated Sonic Hedgehog (SHH) pathway facilitates the initiation, progression, and metastasis of Non-small cell lung cancer (NSCLC), confers drug resistance and renders a therapeutic interference option to lung cancer patients with poor prognosis. In this study, we screened and evaluated the specificity of a Chinese herb
Scutellariabarbata D....
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Full title
Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP treatment
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TN_cdi_doaj_primary_oai_doaj_org_article_3284c0a2a41c4210bf423c354c810d0c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3284c0a2a41c4210bf423c354c810d0c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-02063-x