Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumat...
Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes
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Author / Creator
Xu, Jing , Jiang, Congshan , Cai, Yongsong , Guo, Yuanxu , Wang, Xipeng , Zhang, Jiaxiang , Xu, Jiawen , Xu, Ke , Zhu, Wenhua , Wang, Si , Zhang, Fujun , Geng, Manman , Han, Yan , Ning, Qilan , Xu, Peng , Meng, Liesu and Lu, Shemin
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The disruption of metabolic events and changes to nutrient and oxygen availability due to sustained inflammation in RA increases the demand of bioenergetic and biosynthetic processes within the damaged tissue. The current study aimed to understand the molecular mechanisms of SLC7A5 (amino acid transporter) in synoviocytes of RA patients.
Synovia...
Alternative Titles
Full title
Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_32a38bbf4ff042e5a0096b449f13f9f3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_32a38bbf4ff042e5a0096b449f13f9f3
Other Identifiers
ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-020-02296-8
