GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in...
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
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Author / Creator
Franceschini, Nora , Giambartolomei, Claudia , de Vries, Paul S. , Bis, Joshua C. , Winkler, Thomas W. , Graff, Misa , Kavousi, Maryam , Dale, Caroline , Hofer, Edith , van Leeuwen, Elisabeth M. , Nolte, Ilja M. , Lu, Lingyi , Pitkänen, Niina , Franzén, Oscar , Hwang, Shih-Jen , Musani, Solomon K. , Schminke, Ulf , Palmas, Walter , Isaacs, Aaron , Correa, Adolfo , Zonderman, Alan B. , Uitterlinden, André G. , Wong, Andrew , Britton, Annie , Ruusalepp, Arno , Sennblad, Bengt , Hedblad, Bo , Pasaniuc, Bogdan , Penninx, Brenda W. , Tzourio, Christophe , Fava, Cristiano , Baldassarre, Damiano , O’Leary, Daniel H. , Tremoli, Elena , Schadt, Eric E. , Ingelsson, Erik , Veglia, Fabrizio , Rivadeneira, Fernando , Beutner, Frank , Chauhan, Ganesh , Heiss, Gerardo , Snieder, Harold , Völzke, Henry , Markus, Hugh S. , Deary, Ian J. , Price, Jacqueline , Hopewell, Jemma C. , Thiery, Joachim , Engmann, Jorgen , Rice, Kenneth , Taylor, Kent D. , Dhana, Klodian , Lind, Lars , Holdt, Lesca M. , Dörr, Marcus , Dichgans, Martin , Kivimaki, Mika , Melander, Olle , Raitakari, Olli , Franco, Oscar H. , Rueda-Ochoa, Oscar L. , Roussos, Panos , Whincup, Peter H. , Giral, Philippe , Rauramaa, Rainer , Burkhardt, Ralph , Wannamethee, S. Goya , McLachlan, Stela , Trompet, Stella , Seshadri, Sudha , Kurl, Sudhir , Ring, Susan , Harris, Tamara B. , Lehtimäki, Terho , Galesloot, Tessel E. , Shah, Tina , Plagnol, Vincent , Rosamond, Wayne D. , Post, Wendy , Zhu, Xiaofeng , Dehghan, Abbas , Seldenrijk, Adrie , Morrison, Alanna C. , Hamsten, Anders , Psaty, Bruce M. , Lawlor, Deborah A. , Schmidt, Helena , Wilson, James F. , Rotter, Jerome I. , Wardlaw, Joanna M. , Deanfield, John , Loeffler, Markus , Debette, Stéphanie , Humphries, Steve E. , Völker, Uwe , Gudnason, Vilmundur , Hingorani, Aroon D. , Björkegren, Johan L. M. , Casas, Juan P. , O’Donnell, Christopher J. , MEGASTROKE Consortium , Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap , Göteborgs universitet , Gothenburg University , Institute of Biomedicine, Department of Pathology , Core Facilities, Bioinformatics , Sahlgrenska Academy , Institutionen för biomedicin, avdelningen för patologi , Sahlgrenska akademin , Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and et al
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in 71,128 individuals for cIMT, and 48,434 individuals for carotid plaque traits. We identify eight n...
Alternative Titles
Full title
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
Authors, Artists and Contributors
Author / Creator
Giambartolomei, Claudia
de Vries, Paul S.
Bis, Joshua C.
Winkler, Thomas W.
Graff, Misa
Kavousi, Maryam
Dale, Caroline
Hofer, Edith
van Leeuwen, Elisabeth M.
Nolte, Ilja M.
Lu, Lingyi
Pitkänen, Niina
Franzén, Oscar
Hwang, Shih-Jen
Musani, Solomon K.
Schminke, Ulf
Palmas, Walter
Isaacs, Aaron
Correa, Adolfo
Zonderman, Alan B.
Uitterlinden, André G.
Wong, Andrew
Britton, Annie
Ruusalepp, Arno
Sennblad, Bengt
Hedblad, Bo
Pasaniuc, Bogdan
Penninx, Brenda W.
Tzourio, Christophe
Fava, Cristiano
Baldassarre, Damiano
O’Leary, Daniel H.
Tremoli, Elena
Schadt, Eric E.
Ingelsson, Erik
Veglia, Fabrizio
Rivadeneira, Fernando
Beutner, Frank
Chauhan, Ganesh
Heiss, Gerardo
Snieder, Harold
Völzke, Henry
Markus, Hugh S.
Deary, Ian J.
Price, Jacqueline
Hopewell, Jemma C.
Thiery, Joachim
Engmann, Jorgen
Rice, Kenneth
Taylor, Kent D.
Dhana, Klodian
Lind, Lars
Holdt, Lesca M.
Dörr, Marcus
Dichgans, Martin
Kivimaki, Mika
Melander, Olle
Raitakari, Olli
Franco, Oscar H.
Rueda-Ochoa, Oscar L.
Roussos, Panos
Whincup, Peter H.
Giral, Philippe
Rauramaa, Rainer
Burkhardt, Ralph
Wannamethee, S. Goya
McLachlan, Stela
Trompet, Stella
Seshadri, Sudha
Kurl, Sudhir
Ring, Susan
Harris, Tamara B.
Lehtimäki, Terho
Galesloot, Tessel E.
Shah, Tina
Plagnol, Vincent
Rosamond, Wayne D.
Post, Wendy
Zhu, Xiaofeng
Dehghan, Abbas
Seldenrijk, Adrie
Morrison, Alanna C.
Hamsten, Anders
Psaty, Bruce M.
Lawlor, Deborah A.
Schmidt, Helena
Wilson, James F.
Rotter, Jerome I.
Wardlaw, Joanna M.
Deanfield, John
Loeffler, Markus
Debette, Stéphanie
Humphries, Steve E.
Völker, Uwe
Gudnason, Vilmundur
Hingorani, Aroon D.
Björkegren, Johan L. M.
Casas, Juan P.
O’Donnell, Christopher J.
MEGASTROKE Consortium
Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap
Göteborgs universitet
Gothenburg University
Institute of Biomedicine, Department of Pathology
Core Facilities, Bioinformatics
Sahlgrenska Academy
Institutionen för biomedicin, avdelningen för patologi
Sahlgrenska akademin
Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
et al
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_32fac89a43804269804a3e18ff002db4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_32fac89a43804269804a3e18ff002db4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07340-5
