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Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar sa...

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar sa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_332640b7f2f048bebeba04c9ee651443

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

About this item

Full title

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-09, Vol.10 (1), p.4176-19, Article 4176

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome abnormalities are frequently observed in cancer, but little is known of their origin and about pathways affecting centrosome homeostasis. Here we show that autophagy preserves centrosome organization and stability through se...

Alternative Titles

Full title

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_332640b7f2f048bebeba04c9ee651443

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_332640b7f2f048bebeba04c9ee651443

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-12094-9

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