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Preclinical development of a miR-132 inhibitor for heart failure treatment

Preclinical development of a miR-132 inhibitor for heart failure treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33579ddb7f504de8ad9792e4fd12c4d2

Preclinical development of a miR-132 inhibitor for heart failure treatment

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Despite proven efficacy of pharmacotherapies targeting primarily global neurohormonal dysregulation, heart failure (HF) is a growing pandemic with increasing burden. Treatments mechanistically focusing at the cardiomyocyte level are lacking. MicroRNAs (miRNA) are transcriptional regulators and essential drivers of disease progression. We previously...

Alternative Titles

Full title

Preclinical development of a miR-132 inhibitor for heart failure treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_33579ddb7f504de8ad9792e4fd12c4d2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33579ddb7f504de8ad9792e4fd12c4d2

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-14349-2

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