Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Like its parent base 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) is a direct epigenetic modification of cytosines in the context of CpG dinucleotides. 5hmC is the most abundant oxidized form of 5mC, generated through the action of TET dioxygenases at gene bodies of actively-transcribed genes and at active or lineage-specific enhancers. A...
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Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
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TN_cdi_doaj_primary_oai_doaj_org_article_3372113a192c47d8b4f10805fe3b75a1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3372113a192c47d8b4f10805fe3b75a1
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-024-03273-z
