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Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S P...

Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34ae0637a2cd4bcf8f28c5b290a95ecd

Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease

About this item

Full title

Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-11, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The most frequent missense mutations in familial Parkinson's disease (PD) occur in the highly conserved
gene with G2019S mutation. We previously established a fly model of PD carrying the
mutation that exhibited the parkinsonism-like phenotypes. An herbal medicine
Blume (GE), has been reported to have neuroprotective effects in toxin-induc...

Alternative Titles

Full title

Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_34ae0637a2cd4bcf8f28c5b290a95ecd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34ae0637a2cd4bcf8f28c5b290a95ecd

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.73753

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