A multi-step nucleation process determines the kinetics of prion-like domain phase separation
A multi-step nucleation process determines the kinetics of prion-like domain phase separation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Compartmentalization by liquid-liquid phase separation (LLPS) has emerged as a ubiquitous mechanism underlying the organization of biomolecules in space and time. Here, we combine rapid-mixing time-resolved small-angle X-ray scattering (SAXS) approaches to characterize the assembly kinetics of a prototypical prion-like domain with equilibrium techn...
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A multi-step nucleation process determines the kinetics of prion-like domain phase separation
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TN_cdi_doaj_primary_oai_doaj_org_article_3515d63866274f01b905879042d061a9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3515d63866274f01b905879042d061a9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24727-z
