Sequence variants influencing the regulation of serum IgG subclass levels
Sequence variants influencing the regulation of serum IgG subclass levels
About this item
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Author / Creator
Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , StemTherapy: National Initiative on Stem Cells for Regenerative Therapy , Department of Laboratory Medicine , Division of Hematology and Clinical Immunology , Avdelningen för hematologi och klinisk immunologi , EpiHealth: Epidemiology for Health , Hematogenomics , Strategic research areas (SRA) , Lunds universitet , Profilområden och andra starka forskningsmiljöer , Lund University , Institutionen för laboratoriemedicin , Profile areas and other strong research environments , Olafsdottir, Thorunn A. , Thorleifsson, Gudmar , Lopez de Lapuente Portilla, Aitzkoa , Jonsson, Stefan , Stefansdottir, Lilja , Niroula, Abhishek , Jonasdottir, Aslaug , Eggertsson, Hannes P. , Halldorsson, Gisli H. , Thorlacius, Gudny E. , Arnthorsson, Asgeir O. , Bjornsdottir, Unnur S. , Asselbergs, Folkert W. , Bentlage, Arthur E. H. , Eyjolfsson, Gudmundur I. , Gudmundsdottir, Steinunn , Gunnarsdottir, Kristbjorg , Halldorsson, Bjarni V. , Holm, Hilma , Ludviksson, Bjorn R. , Melsted, Pall , Norddahl, Gudmundur L. , Olafsson, Isleifur , Saevarsdottir, Saedis , Sigurdardottir, Olof , Sigurdsson, Asgeir , Temming, Robin , Önundarson, Pall T. , Thorsteinsdottir, Unnur , Vidarsson, Gestur , Sulem, Patrick , Gudbjartsson, Daniel F. , Jonsdottir, Ingileif , Nilsson, Björn and Stefansson, Kari
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy chain locus (IGH). Here, we report a genome-wide association study on blood IgG subclass levels. Across 4334 adults and 4571 individuals under 18 years, we discover ten...
Alternative Titles
Full title
Sequence variants influencing the regulation of serum IgG subclass levels
Authors, Artists and Contributors
Author / Creator
Medicinska fakulteten
Strategiska forskningsområden (SFO)
StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
Department of Laboratory Medicine
Division of Hematology and Clinical Immunology
Avdelningen för hematologi och klinisk immunologi
EpiHealth: Epidemiology for Health
Hematogenomics
Strategic research areas (SRA)
Lunds universitet
Profilområden och andra starka forskningsmiljöer
Lund University
Institutionen för laboratoriemedicin
Profile areas and other strong research environments
Olafsdottir, Thorunn A.
Thorleifsson, Gudmar
Lopez de Lapuente Portilla, Aitzkoa
Jonsson, Stefan
Stefansdottir, Lilja
Niroula, Abhishek
Jonasdottir, Aslaug
Eggertsson, Hannes P.
Halldorsson, Gisli H.
Thorlacius, Gudny E.
Arnthorsson, Asgeir O.
Bjornsdottir, Unnur S.
Asselbergs, Folkert W.
Bentlage, Arthur E. H.
Eyjolfsson, Gudmundur I.
Gudmundsdottir, Steinunn
Gunnarsdottir, Kristbjorg
Halldorsson, Bjarni V.
Holm, Hilma
Ludviksson, Bjorn R.
Melsted, Pall
Norddahl, Gudmundur L.
Olafsson, Isleifur
Saevarsdottir, Saedis
Sigurdardottir, Olof
Sigurdsson, Asgeir
Temming, Robin
Önundarson, Pall T.
Thorsteinsdottir, Unnur
Vidarsson, Gestur
Sulem, Patrick
Gudbjartsson, Daniel F.
Jonsdottir, Ingileif
Nilsson, Björn
Stefansson, Kari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_355943621ae84500945b3eafee4e0e12
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_355943621ae84500945b3eafee4e0e12
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52470-8
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