Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A met...
Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations
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Author / Creator
Chen, Fei , Darst, Burcu F , Madduri, Ravi K , Rodriguez, Alex A , Sheng, Xin , Rentsch, Christopher T , Andrews, Caroline , Tang, Wei , Kibel, Adam S , Plym, Anna , Cho, Kelly , Jalloh, Mohamed , Gueye, Serigne Magueye , Niang, Lamine , Ogunbiyi, Olufemi J , Popoola, Olufemi , Adebiyi, Akindele O , Aisuodionoe-Shadrach, Oseremen I , Ajibola, Hafees O , Jamda, Mustapha A , Oluwole, Olabode P , Nwegbu, Maxwell , Adusei, Ben , Mante, Sunny , Darkwa-Abrahams, Afua , Mensah, James E , Adjei, Andrew Anthony , Diop, Halimatou , Lachance, Joseph , Rebbeck, Timothy R , Ambs, Stefan , Gaziano, J Michael , Justice, Amy C , Conti, David V and Haiman, Christopher A
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
We recently developed a multi-ancestry polygenic risk score (PRS) that effectively stratifies prostate cancer risk across populations. In this study, we validated the performance of the PRS in the multi-ancestry Million Veteran Program and additional independent studies.
Within each ancestry population, the association of PRS with prostate cance...
Alternative Titles
Full title
Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations
Authors, Artists and Contributors
Author / Creator
Darst, Burcu F
Madduri, Ravi K
Rodriguez, Alex A
Sheng, Xin
Rentsch, Christopher T
Andrews, Caroline
Tang, Wei
Kibel, Adam S
Plym, Anna
Cho, Kelly
Jalloh, Mohamed
Gueye, Serigne Magueye
Niang, Lamine
Ogunbiyi, Olufemi J
Popoola, Olufemi
Adebiyi, Akindele O
Aisuodionoe-Shadrach, Oseremen I
Ajibola, Hafees O
Jamda, Mustapha A
Oluwole, Olabode P
Nwegbu, Maxwell
Adusei, Ben
Mante, Sunny
Darkwa-Abrahams, Afua
Mensah, James E
Adjei, Andrew Anthony
Diop, Halimatou
Lachance, Joseph
Rebbeck, Timothy R
Ambs, Stefan
Gaziano, J Michael
Justice, Amy C
Conti, David V
Haiman, Christopher A
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_357704951c834856af7fc63a759e4c2d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_357704951c834856af7fc63a759e4c2d
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.78304
