Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation a...
Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination
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Author / Creator
Wang, Yao , Sadike, Dilinuer , Huang, Bo , Li, Ping , Wu, Qiao , Jiang, Na , Fang, Yongkang , Song, Guini , Xu, Li , Wang, Wei and Xie, Minjie
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
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Scope and Contents
Contents
Demyelination occurs in multiple central nervous system (CNS) disorders and is tightly associated with neuroinflammation. Pyroptosis is a form of pro-inflammatory and lytic cell death which has been observed in CNS diseases recently. Regulatory T cells (Tregs) have exhibited immunoregulatory and protective effects in CNS diseases. However, the role...
Alternative Titles
Full title
Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_35e7bf719a0443b99139760c088af362
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35e7bf719a0443b99139760c088af362
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02721-0
