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Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to hi...

Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to hi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35f2710a01ef44dcac93a789319da3a3

Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to high-level amoxicillin resistance of Helicobacter pylori

About this item

Full title

Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to high-level amoxicillin resistance of Helicobacter pylori

Publisher

United States: American Society for Microbiology

Journal title

mSphere, 2024-08, Vol.9 (8), p.e0008924

Language

English

Formats

Publication information

Publisher

United States: American Society for Microbiology

More information

Scope and Contents

Contents

The growing resistance to amoxicillin (AMX)-one of the main antibiotics used in
eradication therapy-is an increasing health concern. Several mutations of penicillin-binding protein 1A (PBP1A) are suspected of causing AMX resistance; however, only a limited set of these mutations have been experimentally explored. This study aimed to investigate...

Alternative Titles

Full title

Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to high-level amoxicillin resistance of Helicobacter pylori

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_35f2710a01ef44dcac93a789319da3a3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35f2710a01ef44dcac93a789319da3a3

Other Identifiers

ISSN

2379-5042

E-ISSN

2379-5042

DOI

10.1128/msphere.00089-24

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