Remodeling articular immune homeostasis with an efferocytosis-informed nanoimitator mitigates rheuma...
Remodeling articular immune homeostasis with an efferocytosis-informed nanoimitator mitigates rheumatoid arthritis in mice
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Zhang, Shengchang , Liu, Ying , Jing, Weiqiang , Chai, Qihao , Tang, Chunwei , Li, Ziyang , Man, Zhentao , Chen, Chen , Zhang, Jing , Sun, Peng , Zhang, Rui , Yang, Zhenmei , Han, Maosen , Wang, Yan , Wei, Xia , Li, Jun , Li, Wei , Abdalla, Mohnad , Yu, Gongchang , Shi, Bin , Zhang, Yuankai , Zhao, Kun and Jiang, Xinyi
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Massive intra-articular infiltration of proinflammatory macrophages is a prominent feature of rheumatoid arthritis (RA) lesions, which are thought to underlie articular immune dysfunction, severe synovitis and ultimately joint erosion. Here we report an efferocytosis-informed nanoimitator (EINI) for in situ targeted reprogramming of synovial inflam...
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Full title
Remodeling articular immune homeostasis with an efferocytosis-informed nanoimitator mitigates rheumatoid arthritis in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_3616fe9a018e4bd2b78df3db34eee873
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3616fe9a018e4bd2b78df3db34eee873
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36468-2
