Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration
Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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Caloric restriction (CR), fasting, and exercise have long been recognized for their neuroprotective and lifespan-extending properties; however, the underlying mechanisms of these phenomena remain elusive. Such extraordinary benefits might be linked to the activation of sirtuins. In mammals, the sirtuin family has seven members (SIRT1-7), which dive...
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Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_364a00071a9d4f51a8f80b1189ea2f1e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_364a00071a9d4f51a8f80b1189ea2f1e
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2013.00048
