Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypotherm...
Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses
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Author / Creator
Silverman, Harold A. , Tynan, Aisling , Hepler, Tyler D. , Chang, Eric H. , Gunasekaran, Manojkumar , Li, Jian Hua , Huerta, Tomás S. , Tsaava, Tea , Chang, Qing , Addorisio, Meghan E. , Chen, Adrian C. , Thompson, Dane A. , Pavlov, Valentin A. , Brines, Michael , Tracey, Kevin J. and Chavan, Sangeeta S.
Publisher
England: BioMed Central
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English
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Publisher
England: BioMed Central
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Contents
Inflammation, the physiological response to infection and injury, is coordinated by the immune and nervous systems. Interleukin-1β (IL-1β) and other cytokines produced during inflammatory responses activate sensory neurons (nociceptors) to mediate the onset of pain, sickness behavior, and metabolic responses. Although nociceptors expressing Transie...
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Full title
Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses
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TN_cdi_doaj_primary_oai_doaj_org_article_371e534ad34c4f0f8c84b787b0e56ebe
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_371e534ad34c4f0f8c84b787b0e56ebe
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ISSN
1528-3658,1076-1551
E-ISSN
1528-3658
DOI
10.1186/s10020-022-00590-6