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ArticlesPeer ReviewedFull Text
TRPA1 as a drug target—promise and challenges
Author / Creator:Chen, Jun ; Hackos, David H.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Naunyn-Schmiedeberg's archives of pharmacology, 2015-04, Vol.388 (4), p.451-463
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The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1
Author / Creator:Bertin, Samuel ; Aoki-Nonaka, Yukari ; Lee, Jihyung ; de Jong, Petrus R ; Kim, Peter ; Han, Tiffany ; Yu, Timothy ; To, Keith ; Takahashi, Naoki ; Boland, Brigid S ; Chang, John T ; Ho, Samuel B ; Herdman, Scott ; Corr, Maripat ; Franco, Alessandra ; Sharma, Sonia ; Dong, Hui ; Akopian, Armen N ; Raz, Eyal
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-09, Vol.66 (9), p.1584-1596
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TRPA1 mediates formalin-induced pain
Author / Creator:McNamara, Colleen R ; Mandel-Brehm, Josh ; Bautista, Diana M ; Siemens, Jan ; Deranian, Kari L ; Zhao, Michael ; Hayward, Neil J ; Chong, Jayhong A ; Julius, David ; Moran, Magdalene M ; Fanger, Christopher M
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (33), p.13525-13530
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
Author / Creator:Paulsen, Candice E. ; Armache, Jean-Paul ; Gao, Yuan ; Cheng, Yifan ; Julius, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-04, Vol.520 (7548), p.511-517
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Irritant-evoked activation and calcium modulation of the TRPA1 receptor
Author / Creator:Zhao, Jianhua ; Lin King, John V. ; Paulsen, Candice E. ; Cheng, Yifan ; Julius, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-09, Vol.585 (7823), p.141-145
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TRPA1 and thermosensitivity
Author / Creator:Tominaga, Makoto ; Iwata, Moe
Publisher:United States: Elsevier Inc
Journal title:The journal of physiological sciences, 2025-03, Vol.75 (1), p.100010, Article 100010
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TRPA1 Antagonists for Pain Relief
Author / Creator:Koivisto, Ari ; Jalava, Niina ; Bratty, Raymond ; Pertovaara, Antti
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2018-11, Vol.11 (4), p.117
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No functional TRPA1 in cardiomyocytes
Author / Creator:Hoebart, Clara ; Rojas‐Galvan, Natalia S. ; Ciotu, Cosmin I. ; Aykac, Ibrahim ; Reissig, Lukas F. ; Weninger, Wolfgang J. ; Kiss, Attila ; Podesser, Bruno K. ; Fischer, Michael J. M. ; Heber, Stefan
Publisher:England: Wiley Subscription Services, Inc
Journal title:Acta Physiologica, 2021-08, Vol.232 (4), p.e13659-n/a
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TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol
Author / Creator:Andersson, David A ; Gentry, Clive ; Alenmyr, Lisa ; Killander, Dan ; Lewis, Simon E ; Andersson, Anders ; Bucher, Bernard ; Galzi, Jean-Luc ; Sterner, Olov ; Bevan, Stuart ; Högestätt, Edward D ; Zygmunt, Peter M
Publisher:England
Journal title:Nature communications, 2011, Vol.2, p.551-551
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TRPA1 Expression and Pathophysiology in Immune Cells
Author / Creator:Naert, Robbe ; López-Requena, Alejandro ; Talavera, Karel
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-10, Vol.22 (21), p.11460
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Roles of tumor necrosis factor-α and interleukin-6 in regulating bone cancer pain via TRPA1 signal pathway and beneficial effects of inhibition of neuro-inflammation and TRPA1
Author / Creator:Zhao, Ding ; Han, Dong-Feng ; Wang, Si-Si ; Lv, Bing ; Wang, Xu ; Ma, Chi
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Molecular pain, 2019-01, Vol.15, p.1744806919857981-1744806919857981
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TRPA1 underlies a sensing mechanism for O2
Author / Creator:Takahashi, Nobuaki ; Kuwaki, Tomoyuki ; Kiyonaka, Shigeki ; Numata, Tomohiro ; Kozai, Daisuke ; Mizuno, Yusuke ; Yamamoto, Shinichiro ; Naito, Shinji ; Knevels, Ellen ; Carmeliet, Peter ; Oga, Toru ; Kaneko, Shuji ; Suga, Seiji ; Nokami, Toshiki ; Yoshida, Jun-ichi ; Mori, Yasuo
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2011-08, Vol.7 (10), p.701-711
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Research Progress on TRPA1 in Diseases
Author / Creator:Li, Jiajing ; Zhang, Hongfei ; Du, Qian ; Gu, Junyu ; Wu, Jiangbo ; Liu, Qi ; Li, Zhuo ; Zhang, Ting ; Xu, Jingyu ; Xie, Rui
Publisher:New York: Springer US
Journal title:The Journal of membrane biology, 2023-12, Vol.256 (4-6), p.301-316
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Brain endothelial cell TRPA1 channels initiate neurovascular coupling
Author / Creator:Thakore, Pratish ; Alvarado, Michael G ; Ali, Sher ; Mughal, Amreen ; Pires, Paulo W ; Yamasaki, Evan ; Pritchard, Harry AT ; Isakson, Brant E ; Tran, Cam Ha T ; Earley, Scott
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-02, Vol.10
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Methylglyoxal Evokes Pain by Stimulating TRPA1
Author / Creator:Andersson, David A. ; Gentry, Clive ; Light, Emily ; Vastani, Nisha ; Vallortigara, Julie ; Bierhaus, Angelika ; Fleming, Thomas ; Bevan, Stuart
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e77986
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Species differences and molecular determinant of TRPA1 cold sensitivity
Author / Creator:Chen, Jun ; Kang, Dawon ; Xu, Jing ; Lake, Marc ; Hogan, James O. ; Sun, Chaohong ; Walter, Karl ; Yao, Betty ; Kim, Donghee
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013-09, Vol.4 (1), p.2501, Article 2501
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TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation： pro-inflammatory response induced by their activation and their sensitization
Author / Creator:Gouin, Olivier ; L’Herondelle, Killian ; Lebonvallet, Nicolas ; Le Gall-Ianotto, Christelle ; Sakka, Mehdi ; Buhé, Virginie ; Plée-Gautier, Emmanuelle ; Carré, Jean-Luc ; Lefeuvre, Luc ; Misery, Laurent ; Le Garrec, Raphaele
Publisher:Beijing: Higher Education Press
Journal title:Protein & cell, 2017-09, Vol.8 (9), p.644-661
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Direct evidence for functional TRPV1/TRPA1 heteromers
Author / Creator:Fischer, Michael J. M. ; Balasuriya, Dilshan ; Jeggle, Pia ; Goetze, Tom A. ; McNaughton, Peter A. ; Reeh, Peter W. ; Edwardson, J. Michael
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Pflügers Archiv, 2014-12, Vol.466 (12), p.2229-2241
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Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice
Author / Creator:De Logu, Francesco ; Nassini, Romina ; Materazzi, Serena ; Carvalho Gonçalves, Muryel ; Nosi, Daniele ; Rossi Degl’Innocenti, Duccio ; Marone, Ilaria M. ; Ferreira, Juliano ; Li Puma, Simone ; Benemei, Silvia ; Trevisan, Gabriela ; Souza Monteiro de Araújo, Daniel ; Patacchini, Riccardo ; Bunnett, Nigel W. ; Geppetti, Pierangelo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.1887-16, Article 1887
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Cigarette smoke–induced neurogenic inflammation is mediated by α,β-unsaturated aldehydes and the TRPA1 receptor in rodents
Author / Creator:Andrè, Eunice ; Campi, Barbara ; Materazzi, Serena ; Trevisani, Marcello ; Amadesi, Silvia ; Massi, Daniela ; Creminon, Christophe ; Vaksman, Natalya ; Nassini, Romina ; Civelli, Maurizio ; Baraldi, Pier Giovanni ; Poole, Daniel P. ; Bunnett, Nigel W. ; Geppetti, Pierangelo ; Patacchini, Riccardo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2008-07, Vol.118 (7), p.2574-2582
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Showing 1 to 20 of 2,507 results

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TRPA1 as a drug target—promise and challenges

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The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1

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TRPA1 mediates formalin-induced pain

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Structure of the TRPA1 ion channel suggests regulatory mechanisms

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Irritant-evoked activation and calcium modulation of the TRPA1 receptor

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TRPA1 and thermosensitivity

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TRPA1 Antagonists for Pain Relief

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No functional TRPA1 in cardiomyocytes

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TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol

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TRPA1 Expression and Pathophysiology in Immune Cells

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Roles of tumor necrosis factor-α and interleukin-6 in regulating bone cancer pain via TRPA1 signal pathway and beneficial effects of inhibition of neuro-inflammation and TRPA1

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TRPA1 underlies a sensing mechanism for O2

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Research Progress on TRPA1 in Diseases

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Brain endothelial cell TRPA1 channels initiate neurovascular coupling

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Methylglyoxal Evokes Pain by Stimulating TRPA1

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Species differences and molecular determinant of TRPA1 cold sensitivity

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TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation： pro-inflammatory response induced by their activation and their sensitization

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Direct evidence for functional TRPV1/TRPA1 heteromers

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Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

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Cigarette smoke–induced neurogenic inflammation is mediated by α,β-unsaturated aldehydes and the TRPA1 receptor in rodents

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