TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Di...
TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome
About this item
Full title
Author / Creator
Werren, Elizabeth A. , LaForce, Geneva R. , Srivastava, Anshika , Perillo, Delia R. , Li, Shaokun , Johnson, Katherine , Baris, Safa , Berger, Brandon , Regan, Samantha L. , Pfennig, Christian D. , de Munnik, Sonja , Pfundt, Rolph , Hebbar, Malavika , Jimenez-Heredia, Raúl , Karakoc-Aydiner, Elif , Ozen, Ahmet , Dmytrus, Jasmin , Krolo, Ana , Corning, Ken , Prijoles, E. J. , Louie, Raymond J. , Lebel, Robert Roger , Le, Thuy-Linh , Amiel, Jeanne , Gordon, Christopher T. , Boztug, Kaan , Girisha, Katta M. , Shukla, Anju , Bielas, Stephanie L. and Schaffer, Ashleigh E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
THOC6
variants are the genetic basis of autosomal recessive
THOC6
Intellectual Disability Syndrome (TIDS). THOC6 is critical for mammalian Transcription Export complex (TREX) tetramer formation, which is composed of four six-subunit THO monomers. The TREX tetramer facilitates mammalian RNA processing, in addition to the nuclear mRNA export...
Alternative Titles
Full title
TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome
Authors, Artists and Contributors
Author / Creator
LaForce, Geneva R.
Srivastava, Anshika
Perillo, Delia R.
Li, Shaokun
Johnson, Katherine
Baris, Safa
Berger, Brandon
Regan, Samantha L.
Pfennig, Christian D.
de Munnik, Sonja
Pfundt, Rolph
Hebbar, Malavika
Jimenez-Heredia, Raúl
Karakoc-Aydiner, Elif
Ozen, Ahmet
Dmytrus, Jasmin
Krolo, Ana
Corning, Ken
Prijoles, E. J.
Louie, Raymond J.
Lebel, Robert Roger
Le, Thuy-Linh
Amiel, Jeanne
Gordon, Christopher T.
Boztug, Kaan
Girisha, Katta M.
Shukla, Anju
Bielas, Stephanie L.
Schaffer, Ashleigh E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_377fd67c893b4d0eba289bde1408f26e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_377fd67c893b4d0eba289bde1408f26e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45948-y
