Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse...
Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content
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Author / Creator
Hatakeyama, Keiichi , Muramatsu, Koji , Nagashima, Takeshi , Ichida, Hiroyuki , Kawanishi, Yuichi , Fukumura, Ryutaro , Ohshima, Keiichi , Shimoda, Yuji , Ohnami, Sumiko , Ohnami, Shumpei , Maruyama, Koji , Naruoka, Akane , Kenmotsu, Hirotsugu , Urakami, Kenichi , Akiyama, Yasuto , Sugino, Takashi and Yamaguchi, Ken
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The detection of copy number variations (CNVs) and somatic mutations in cancer is important for the selection of specific drugs for patients with cancer. In cancers with sporadic tumor cells, low tumor content prevents the accurate detection of somatic alterations using targeted sequencing. To efficiently identify CNVs, we performed tumor cell enri...
Alternative Titles
Full title
Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3803f9f730f74fb287285c07c11200a5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3803f9f730f74fb287285c07c11200a5
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-64541-3
