Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodeling
Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodeling
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Wu, Yichao , Li, Changbiao , Khan, Abid Ali , Chen, Kangchen , Su, Renyi , Xu, Shengjun , Sun, Yiyang , Gao, Fengqiang , Wang, Kai , Wang, Xiaodong , Lian, Zhengxing , Wang, Shuo , Yu, Mengyuan , Hu, Xin , Yang, Fan , Zheng, Shusen , Qiu, Nasha , Liu, Zhikun and Xu, Xiao
Publisher
London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Hepatic ischemia-reperfusion (IR) injury is the primary reason for complications following hepatectomy and liver transplantation (LT). Insulin-induced gene 2 (Insig2) is one of several proteins that anchor the reticulum in the cytoplasm and is essential for metabolism and inflammatory responses. However, its function in IR injury remains...
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Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodeling
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TN_cdi_doaj_primary_oai_doaj_org_article_38e8a35f26ea412d970c56ef540838f5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38e8a35f26ea412d970c56ef540838f5
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-023-04564-y
