Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcripti...
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
About this item
Full title
Author / Creator
Kneppers, Jeroen , Severson, Tesa M. , Siefert, Joseph C. , Schol, Pieter , Joosten, Stacey E. P. , Yu, Ivan Pak Lok , Huang, Chia-Chi Flora , Morova, Tunç , Altıntaş, Umut Berkay , Giambartolomei, Claudia , Seo, Ji-Heui , Baca, Sylvan C. , Carneiro, Isa , Emberly, Eldon , Pasaniuc, Bogdan , Jerónimo, Carmen , Henrique, Rui , Freedman, Matthew L. , Wessels, Lodewyk F. A. , Lack, Nathan A. , Bergman, Andries M. and Zwart, Wilbert
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Androgen receptor (AR) drives prostate cancer (PCa) development and progression. AR chromatin binding profiles are highly plastic and form recurrent programmatic changes that differentiate disease stages, subtypes and patient outcomes. While prior studies focused on concordance between patient subgroups, inter-tumor heterogeneity of AR enhancer sel...
Alternative Titles
Full title
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
Authors, Artists and Contributors
Author / Creator
Severson, Tesa M.
Siefert, Joseph C.
Schol, Pieter
Joosten, Stacey E. P.
Yu, Ivan Pak Lok
Huang, Chia-Chi Flora
Morova, Tunç
Altıntaş, Umut Berkay
Giambartolomei, Claudia
Seo, Ji-Heui
Baca, Sylvan C.
Carneiro, Isa
Emberly, Eldon
Pasaniuc, Bogdan
Jerónimo, Carmen
Henrique, Rui
Freedman, Matthew L.
Wessels, Lodewyk F. A.
Lack, Nathan A.
Bergman, Andries M.
Zwart, Wilbert
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_391fd7851a8744c0932eb78127f219b4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_391fd7851a8744c0932eb78127f219b4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-35135-2
