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97 results for Zwart,+Wilbert

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Genomic and phenotypic heterogeneity in prostate cancer
Author / Creator:Haffner, Michael C. ; Zwart, Wilbert ; Roudier, Martine P. ; True, Lawrence D. ; Nelson, William G. ; Epstein, Jonathan I. ; De Marzo, Angelo M. ; Nelson, Peter S. ; Yegnasubramanian, Srinivasan
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Urology, 2021-02, Vol.18 (2), p.79-92
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Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
Author / Creator:Korkmaz, Gozde ; Lopes, Rui ; Ugalde, Alejandro P ; Nevedomskaya, Ekaterina ; Han, Ruiqi ; Myacheva, Ksenia ; Zwart, Wilbert ; Elkon, Ran ; Agami, Reuven
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2016-02, Vol.34 (2), p.192-198
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The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer
Author / Creator:Hickey, Theresa E. ; Selth, Luke A. ; Chia, Kee Ming ; Laven-Law, Geraldine ; Milioli, Heloisa H. ; Roden, Daniel ; Jindal, Shalini ; Hui, Mun ; Finlay-Schultz, Jessica ; Ebrahimie, Esmaeil ; Birrell, Stephen N. ; Stelloo, Suzan ; Iggo, Richard ; Alexandrou, Sarah ; Caldon, C. Elizabeth ; Abdel-Fatah, Tarek M. ; Ellis, Ian O. ; Zwart, Wilbert ; Palmieri, Carlo ; Sartorius, Carol A. ; Swarbrick, Alex ; Lim, Elgene ; Carroll, Jason S. ; Tilley, Wayne D.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-02, Vol.27 (2), p.310-320
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Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
Author / Creator:Cioni, Bianca ; Zaalberg, Anniek ; van Beijnum, Judy R. ; Melis, Monique H. M. ; van Burgsteden, Johan ; Muraro, Mauro J. ; Hooijberg, Erik ; Peters, Dennis ; Hofland, Ingrid ; Lubeck, Yoni ; de Jong, Jeroen ; Sanders, Joyce ; Vivié, Judith ; van der Poel, Henk G. ; de Boer, Jan Paul ; Griffioen, Arjan W. ; Zwart, Wilbert ; Bergman, Andries M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-09, Vol.11 (1), p.4498-4498, Article 4498
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The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
Author / Creator:Shafi, Ayesha A. ; McNair, Chris M. ; McCann, Jennifer J. ; Alshalalfa, Mohammed ; Shostak, Anton ; Severson, Tesa M. ; Zhu, Yanyun ; Bergman, Andre ; Gordon, Nicolas ; Mandigo, Amy C. ; Chand, Saswati N. ; Gallagher, Peter ; Dylgjeri, Emanuela ; Laufer, Talya S. ; Vasilevskaya, Irina A. ; Schiewer, Matthew J. ; Brunner, Michael ; Feng, Felix Y. ; Zwart, Wilbert ; Knudsen, Karen E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.401-15, Article 401
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Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin
Author / Creator:Pang, Baoxu ; Qiao, Xiaohang ; Janssen, Lennert ; Velds, Arno ; Groothuis, Tom ; Kerkhoven, Ron ; Nieuwland, Marja ; Ovaa, Huib ; Rottenberg, Sven ; van Tellingen, Olaf ; Janssen, Jeroen ; Huijgens, Peter ; Zwart, Wilbert ; Neefjes, Jacques
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013-05, Vol.4 (1), p.1908, Article 1908
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An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer
Author / Creator:Davies, Alastair ; Nouruzi, Shaghayegh ; Ganguli, Dwaipayan ; Namekawa, Takeshi ; Thaper, Daksh ; Linder, Simon ; Karaoğlanoğlu, Fatih ; Omur, Meltem E. ; Kim, Soojin ; Kobelev, Maxim ; Kumar, Sahil ; Sivak, Olena ; Bostock, Chiara ; Bishop, Jennifer ; Hoogstraat, Marlous ; Talal, Amina ; Stelloo, Suzan ; van der Poel, Henk ; Bergman, Andries M. ; Ahmed, Musaddeque ; Fazli, Ladan ; Huang, Haojie ; Tilley, Wayne ; Goodrich, David ; Feng, Felix Y. ; Gleave, Martin ; He, Housheng Hansen ; Hach, Faraz ; Zwart, Wilbert ; Beltran, Himisha ; Selth, Luke ; Zoubeidi, Amina
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2021-09, Vol.23 (9), p.1023-1034
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The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact
Author / Creator:van Dessel, Lisanne F. ; van Riet, Job ; Smits, Minke ; Zhu, Yanyun ; Hamberg, Paul ; van der Heijden, Michiel S. ; Bergman, Andries M. ; van Oort, Inge M. ; de Wit, Ronald ; Voest, Emile E. ; Steeghs, Neeltje ; Yamaguchi, Takafumi N. ; Livingstone, Julie ; Boutros, Paul C. ; Martens, John W. M. ; Sleijfer, Stefan ; Cuppen, Edwin ; Zwart, Wilbert ; van de Werken, Harmen J. G. ; Mehra, Niven ; Lolkema, Martijn P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-11, Vol.10 (1), p.5251-13, Article 5251
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Integrative epigenetic taxonomy of primary prostate cancer
Author / Creator:Stelloo, Suzan ; Nevedomskaya, Ekaterina ; Kim, Yongsoo ; Schuurman, Karianne ; Valle-Encinas, Eider ; Lobo, João ; Krijgsman, Oscar ; Peeper, Daniel Simon ; Chang, Seiwon Laura ; Feng, Felix Yi-Chung ; Wessels, Lodewyk Frederik Ary ; Henrique, Rui ; Jerónimo, Carmen ; Bergman, Andries Marinus ; Zwart, Wilbert
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-11, Vol.9 (1), p.4900-12, Article 4900
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A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer
Author / Creator:Palit, Sander A. L. ; van Dorp, Jeroen ; Vis, Daniel ; Lieftink, Cor ; Linder, Simon ; Beijersbergen, Roderick ; Bergman, Andries M. ; Zwart, Wilbert ; van der Heijden, Michiel S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-07, Vol.11 (1), p.13683-8, Article 13683
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A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility
Author / Creator:Kedde, Martijn ; van Kouwenhove, Marieke ; Zwart, Wilbert ; Oude Vrielink, Joachim A. F. ; Elkon, Ran ; Agami, Reuven
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2010-10, Vol.12 (10), p.1014-1020
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MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
Author / Creator:Zimmerli, Dario ; Brambillasca, Chiara S. ; Talens, Francien ; Bhin, Jinhyuk ; Linstra, Renske ; Romanens, Lou ; Bhattacharya, Arkajyoti ; Joosten, Stacey E. P. ; Da Silva, Ana Moises ; Padrao, Nuno ; Wellenstein, Max D. ; Kersten, Kelly ; de Boo, Mart ; Roorda, Maurits ; Henneman, Linda ; de Bruijn, Roebi ; Annunziato, Stefano ; van der Burg, Eline ; Drenth, Anne Paulien ; Lutz, Catrin ; Endres, Theresa ; van de Ven, Marieke ; Eilers, Martin ; Wessels, Lodewyk ; de Visser, Karin E. ; Zwart, Wilbert ; Fehrmann, Rudolf S. N. ; van Vugt, Marcel A. T. M. ; Jonkers, Jos
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-11, Vol.13 (1), p.6579-18, Article 6579
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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance
Author / Creator:Martin, Lesley-Ann ; Ribas, Ricardo ; Simigdala, Nikiana ; Schuster, Eugene ; Pancholi, Sunil ; Tenev, Tencho ; Gellert, Pascal ; Buluwela, Laki ; Harrod, Alison ; Thornhill, Allan ; Nikitorowicz-Buniak, Joanna ; Bhamra, Amandeep ; Turgeon, Marc-Olivier ; Poulogiannis, George ; Gao, Qiong ; Martins, Vera ; Hills, Margaret ; Garcia-Murillas, Isaac ; Fribbens, Charlotte ; Patani, Neill ; Li, Zheqi ; Sikora, Matthew J. ; Turner, Nicholas ; Zwart, Wilbert ; Oesterreich, Steffi ; Carroll, Jason ; Ali, Simak ; Dowsett, Mitch
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1865-15, Article 1865
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Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer
Author / Creator:Prekovic, Stefan ; Schuurman, Karianne ; Mayayo-Peralta, Isabel ; Manjón, Anna G. ; Buijs, Mark ; Yavuz, Selçuk ; Wellenstein, Max D. ; Barrera, Alejandro ; Monkhorst, Kim ; Huber, Anne ; Morris, Ben ; Lieftink, Cor ; Chalkiadakis, Theofilos ; Alkan, Ferhat ; Silva, Joana ; Győrffy, Balázs ; Hoekman, Liesbeth ; van den Broek, Bram ; Teunissen, Hans ; Debets, Donna O. ; Severson, Tesa ; Jonkers, Jos ; Reddy, Timothy ; de Visser, Karin E. ; Faller, William ; Beijersbergen, Roderick ; Altelaar, Maarten ; de Wit, Elzo ; Medema, Rene ; Zwart, Wilbert
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.1-18, Article 4360
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Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?
Author / Creator:Zwart, Wilbert ; Terra, Huub ; Linn, Sabine C. ; Schagen, Sanne B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2015-10, Vol.12 (10), p.597-606
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Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation
Author / Creator:Silva, Joana ; Alkan, Ferhat ; Ramalho, Sofia ; Snieckute, Goda ; Prekovic, Stefan ; Garcia, Ana Krotenberg ; Hernández-Pérez, Santiago ; van der Kammen, Rob ; Barnum, Danielle ; Hoekman, Liesbeth ; Altelaar, Maarten ; Zwart, Wilbert ; Suijkerbuijk, Saskia Jacoba Elisabeth ; Bekker-Jensen, Simon ; Faller, William James
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4492-4492, Article 4492
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Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo
Author / Creator:Kim, Yongsoo ; Bismeijer, Tycho ; Zwart, Wilbert ; Wessels, Lodewyk F. A. ; Vis, Daniel J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-11, Vol.10 (1), p.5034-12, Article 5034
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Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis o...
Author / Creator:Kurozumi, Sasagu ; Alsaleem, Mansour ; Monteiro, Cíntia J. ; Bhardwaj, Kartikeya ; Joosten, Stacey E. P. ; Fujii, Takaaki ; Shirabe, Ken ; Green, Andrew R. ; Ellis, Ian O. ; Rakha, Emad A. ; Mongan, Nigel P. ; Heery, David M. ; Zwart, Wilbert ; Oesterreich, Steffi ; Johnston, Simon J.
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2020-08, Vol.22 (1), p.85-85, Article 85
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Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations
Author / Creator:Gregoricchio, Sebastian ; Kojic, Aleksandar ; Hoogstraat, Marlous ; Schuurman, Karianne ; Stelloo, Suzan ; Severson, Tesa M. ; O’Mara, Tracy A. ; Droog, Marjolein ; Singh, Abhishek A. ; Glubb, Dylan M. ; Wessels, Lodewyk F. A. ; Vermeulen, Michiel ; van Leeuwen, Flora E. ; Zwart, Wilbert
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2025-05, Vol.26 (1), p.124-31, Article 124
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Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?
Author / Creator:Beelen, Karin ; Zwart, Wilbert ; Linn, Sabine C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2012-09, Vol.9 (9), p.529-541
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Genomic and phenotypic heterogeneity in prostate cancer

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Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9

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The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer

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Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion

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The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

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Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

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An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer

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The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

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Integrative epigenetic taxonomy of primary prostate cancer

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A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer

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A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility

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MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

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Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer

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Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

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Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

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Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo

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Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis o...

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Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations

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Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

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