α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injec...
α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb
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England: BioMed Central
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English
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England: BioMed Central
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Alpha-synuclein inclusions, the hallmarks of synucleinopathies, are suggested to spread along neuronal connections in a stereotypical pattern in the brains of patients. Ample evidence now supports that pathological forms of alpha-synuclein propagate in cell culture models and in vivo in a prion-like manner. However, it is still not known why the sa...
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α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb
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TN_cdi_doaj_primary_oai_doaj_org_article_392d3687fdd945a8b98109737c3aa20d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_392d3687fdd945a8b98109737c3aa20d
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-019-0859-3
