Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
About this item
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Author / Creator
Gagne, Matthew , Flynn, Barbara J. , Honeycutt, Christopher Cole , Flebbe, Dillon R. , Andrew, Shayne F. , Provost, Samantha J. , McCormick, Lauren , Van Ry, Alex , McCarthy, Elizabeth , Todd, John-Paul M. , Bao, Saran , Teng, I-Ting , Marciano, Shir , Rudich, Yinon , Li, Chunlin , Jain, Shilpi , Wali, Bushra , Pessaint, Laurent , Dodson, Alan , Cook, Anthony , Lewis, Mark G. , Andersen, Hanne , Zahradník, Jiří , Suthar, Mehul S. , Nason, Martha C. , Foulds, Kathryn E. , Kwong, Peter D. , Roederer, Mario , Schreiber, Gideon , Seder, Robert A. and Douek, Daniel C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
SARS-CoV-2 has the capacity to evolve mutations that escape vaccine- and infection-acquired immunity and antiviral drugs. A variant-agnostic therapeutic agent that protects against severe disease without putting selective pressure on the virus would thus be a valuable biomedical tool that would maintain its efficacy despite the ongoing emergence of...
Alternative Titles
Full title
Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
Authors, Artists and Contributors
Author / Creator
Flynn, Barbara J.
Honeycutt, Christopher Cole
Flebbe, Dillon R.
Andrew, Shayne F.
Provost, Samantha J.
McCormick, Lauren
Van Ry, Alex
McCarthy, Elizabeth
Todd, John-Paul M.
Bao, Saran
Teng, I-Ting
Marciano, Shir
Rudich, Yinon
Li, Chunlin
Jain, Shilpi
Wali, Bushra
Pessaint, Laurent
Dodson, Alan
Cook, Anthony
Lewis, Mark G.
Andersen, Hanne
Zahradník, Jiří
Suthar, Mehul S.
Nason, Martha C.
Foulds, Kathryn E.
Kwong, Peter D.
Roederer, Mario
Schreiber, Gideon
Seder, Robert A.
Douek, Daniel C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_398a2dfd9ac6483f881f1a81f6f17840
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_398a2dfd9ac6483f881f1a81f6f17840
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51046-w
