Gasdermin D deficiency aggravates nephrocalcinosis-related chronic kidney disease with rendering mac...
Gasdermin D deficiency aggravates nephrocalcinosis-related chronic kidney disease with rendering macrophages vulnerable to necroptosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Several forms of regulated necrosis contribute to the pathogenesis of crystal nephropathy, however, the role of pyroptosis, an inflammatory form of cell death involving the formation of gasdermin-D pores in internal and external cell membranes, in this condition remains unknown. Our transcriptional and histological analyses suggest that Gsdmd in tu...
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Gasdermin D deficiency aggravates nephrocalcinosis-related chronic kidney disease with rendering macrophages vulnerable to necroptosis
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TN_cdi_doaj_primary_oai_doaj_org_article_39edf185fc3e43d2a2351cf78bee139d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39edf185fc3e43d2a2351cf78bee139d
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-025-07620-1
