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ArticlesPeer ReviewedFull Text
‘Hints’ in the killer protein gasdermin D: unveiling the secrets of gasdermins driving cell death
Author / Creator:Qiu, Shiqiao ; Liu, Jing ; Xing, Feiyue
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-04, Vol.24 (4), p.588-596
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Channelling inflammation: gasdermins in physiology and disease
Author / Creator:Liu, Xing ; Xia, Shiyu ; Zhang, Zhibin ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2021-05, Vol.20 (5), p.384-405
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Gasdermins: making pores for pyroptosis
Author / Creator:Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2021-10, Vol.21 (10), p.620-621
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Gasdermins and pyroptosis in the kidney
Author / Creator:Elias, Esteban E. ; Lyons, Brayden ; Muruve, Daniel A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Nephrology, 2023-05, Vol.19 (5), p.337-350
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The gasdermins, a protein family executing cell death and inflammation
Author / Creator:Broz, Petr ; Pelegrín, Pablo ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2020-03, Vol.20 (3), p.143-157
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Gasdermin splicing
Author / Creator:Bernard, Nicholas J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-06, Vol.24 (6), p.886-886
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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death
Author / Creator:Orning, Pontus ; Weng, Dan ; Starheim, Kristian ; Ratner, Dmitry ; Best, Zachary ; Lee, Bettina ; Brooks, Alexandria ; Xia, Shiyu ; Wu, Hao ; Kelliher, Michelle A ; Berger, Scott B ; Gough, Peter J ; Bertin, John ; Proulx, Megan M ; Goguen, Jon D ; Kayagaki, Nobuhiko ; Fitzgerald, Katherine A ; Lien, Egil
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6418), p.1064-1069
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ArticlesPeer ReviewedFull Text
Gasdermin E suppresses tumour growth by activating anti-tumour immunity
Author / Creator:Zhang, Zhibin ; Zhang, Ying ; Xia, Shiyu ; Kong, Qing ; Li, Shunying ; Liu, Xing ; Junqueira, Caroline ; Meza-Sosa, Karla F. ; Mok, Temy Mo Yin ; Ansara, James ; Sengupta, Satyaki ; Yao, Yandan ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7799), p.415-420
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ArticlesPeer ReviewedFull Text
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Author / Creator:Liu, Xing ; Zhang, Zhibin ; Ruan, Jianbin ; Pan, Youdong ; Magupalli, Venkat Giri ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.153-158
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Gasdermin D pore structure reveals preferential release of mature interleukin-1
Author / Creator:Xia, Shiyu ; Zhang, Zhibin ; Magupalli, Venkat Giri ; Pablo, Juan Lorenzo ; Dong, Ying ; Vora, Setu M. ; Wang, Longfei ; Fu, Tian-Min ; Jacobson, Matthew P. ; Greka, Anna ; Lieberman, Judy ; Ruan, Jianbin ; Wu, Hao
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-05, Vol.593 (7860), p.607-611
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Reference EntriesFull Text
gasdermins
Publisher:Oxford University Press
Journal title:A Dictionary of Biomedicine, 2019
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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
Author / Creator:Wang, Yupeng ; Gao, Wenqing ; Shi, Xuyan ; Ding, Jingjin ; Liu, Wang ; He, Huabin ; Wang, Kun ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-07, Vol.547 (7661), p.99-103
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ArticlesPeer ReviewedFull Text
Pyroptosis, inflammasome, and gasdermins in tumor immunity
Author / Creator:Ouyang, Xiaohu ; Zhou, Junfen ; Lin, Lan ; Zhang, Zili ; Luo, Shanshan ; Hu, Desheng
Publisher:London, England: SAGE Publications
Journal title:Innate immunity (London, England), 2023-01, Vol.29 (1-2), p.3-13
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Pore-forming activity and structural autoinhibition of the gasdermin family
Author / Creator:Ding, Jingjin ; Wang, Kun ; Liu, Wang ; She, Yang ; Sun, Qi ; Shi, Jianjin ; Sun, Hanzi ; Wang, Da-Cheng ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.111-116
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ArticlesPeer ReviewedFull Text
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Author / Creator:He, Wan-ting ; Wan, Haoqiang ; Hu, Lichen ; Chen, Pengda ; Wang, Xin ; Huang, Zhe ; Yang, Zhang-Hua ; Zhong, Chuan-Qi ; Han, Jiahuai
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2015-12, Vol.25 (12), p.1285-1298
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ArticlesPeer ReviewedFull Text
Molecular mechanisms of gasdermin D pore-forming activity
Author / Creator:Devant, Pascal ; Kagan, Jonathan C.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-07, Vol.24 (7), p.1064-1075
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ArticlesPeer ReviewedFull Text
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Author / Creator:Hou, Junwei ; Zhao, Rongce ; Xia, Weiya ; Chang, Chiung-Wen ; You, Yun ; Hsu, Jung-Mao ; Nie, Lei ; Chen, Yeh ; Wang, Yu-Chuan ; Liu, Chunxiao ; Wang, Wei-Jan ; Wu, Yun ; Ke, Baozhen ; Hsu, Jennifer L. ; Huang, Kebin ; Ye, Zu ; Yang, Yi ; Xia, Xianghou ; Li, Yintao ; Li, Chia-Wei ; Shao, Bin ; Tainer, John A. ; Hung, Mien-Chie
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-10, Vol.22 (10), p.1264-1275
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ArticlesPeer ReviewedFull Text
Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor
Author / Creator:Yang, Jie ; Liu, Zhonghua ; Wang, Chuanping ; Yang, Rui ; Rathkey, Joseph K. ; Pinkard, Otis W. ; Shi, Wuxian ; Chen, Yinghua ; Dubyak, George R. ; Abbott, Derek W. ; Xiao, Tsan Sam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.6792-6797
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ArticlesPeer ReviewedFull Text
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Author / Creator:Kayagaki, Nobuhiko ; Stowe, Irma B. ; Lee, Bettina L. ; O’Rourke, Karen ; Anderson, Keith ; Warming, Søren ; Cuellar, Trinna ; Haley, Benjamin ; Roose-Girma, Merone ; Phung, Qui T. ; Liu, Peter S. ; Lill, Jennie R. ; Li, Hong ; Wu, Jiansheng ; Kummerfeld, Sarah ; Zhang, Juan ; Lee, Wyne P. ; Snipas, Scott J. ; Salvesen, Guy S. ; Morris, Lucy X. ; Fitzgerald, Linda ; Zhang, Yafei ; Bertram, Edward M. ; Goodnow, Christopher C. ; Dixit, Vishva M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-10, Vol.526 (7575), p.666-671
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ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D
Author / Creator:Du, Gang ; Healy, Liam B. ; David, Liron ; Walker, Caitlin ; El-Baba, Tarick J. ; Lutomski, Corinne A. ; Goh, Byoungsook ; Gu, Bowen ; Pi, Xiong ; Devant, Pascal ; Fontana, Pietro ; Dong, Ying ; Ma, Xiyu ; Miao, Rui ; Balasubramanian, Arumugam ; Puthenveetil, Robbins ; Banerjee, Anirban ; Luo, Hongbo R. ; Kagan, Jonathan C. ; Oh, Sungwhan F. ; Robinson, Carol V. ; Lieberman, Judy ; Wu, Hao
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2024-06, Vol.630 (8016), p.437-446
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‘Hints’ in the killer protein gasdermin D: unveiling the secrets of gasdermins driving cell death

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Channelling inflammation: gasdermins in physiology and disease

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Gasdermins: making pores for pyroptosis

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Gasdermins and pyroptosis in the kidney

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The gasdermins, a protein family executing cell death and inflammation

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Gasdermin splicing

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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death

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Gasdermin E suppresses tumour growth by activating anti-tumour immunity

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

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Gasdermin D pore structure reveals preferential release of mature interleukin-1

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gasdermins

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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

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Pyroptosis, inflammasome, and gasdermins in tumor immunity

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Pore-forming activity and structural autoinhibition of the gasdermin family

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

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Molecular mechanisms of gasdermin D pore-forming activity

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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

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Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

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ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

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