Experience-dependent serotonergic signaling in glia regulates targeted synapse elimination
Experience-dependent serotonergic signaling in glia regulates targeted synapse elimination
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The optimization of brain circuit connectivity based on initial environmental input occurs during critical periods characterized by sensory experience-dependent, temporally restricted, and transiently reversible synapse elimination. This precise, targeted synaptic pruning mechanism is mediated by glial phagocytosis. Serotonin signaling has prominen...
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Full title
Experience-dependent serotonergic signaling in glia regulates targeted synapse elimination
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TN_cdi_doaj_primary_oai_doaj_org_article_3ac043d189ef4203acb38aad6cb5f4bb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ac043d189ef4203acb38aad6cb5f4bb
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002822
