604 Clinical and molecular findings from a randomized phase II study of epigenetic priming with azac...
604 Clinical and molecular findings from a randomized phase II study of epigenetic priming with azacitidine and entinostat followed by nivolumab in previously treated metastatic non-small cell lung cancer
About this item
Full title
Author / Creator
Marrone, Kristen A , Landon, Blair V , Topper, Michael J , Tsai, Hua-Ling , Balan, Archana , Niknafs, Noushin , Cherry, Christopher , White, James , Hu, Chen , Riemer, Joanne , Fitzpatrick, Margaret , Forde, Patrick , Hann, Christine , Kelly, Ronan , Ettinger, David , Levy, Benjamin , Nieva, Jorge , Herman, James , Velculescu, Victor , Anagnostou, Valsamo , Baylin, Stephen and Brahmer, Julie
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd
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More information
Scope and Contents
Contents
BackgroundEpigenetic targeting agents with immunotherapy represents an ongoing combinatorial approach in non-small cell lung cancer (NSCLC). Preclinical studies have shown that histone deacetylase (HDAC) and/or DNA methyltransferase (DNMT) inhibition can induce susceptibility to immune checkpoint inhibition (ICI), likely via an increase in tumor ce...
Alternative Titles
Full title
604 Clinical and molecular findings from a randomized phase II study of epigenetic priming with azacitidine and entinostat followed by nivolumab in previously treated metastatic non-small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Landon, Blair V
Topper, Michael J
Tsai, Hua-Ling
Balan, Archana
Niknafs, Noushin
Cherry, Christopher
White, James
Hu, Chen
Riemer, Joanne
Fitzpatrick, Margaret
Forde, Patrick
Hann, Christine
Kelly, Ronan
Ettinger, David
Levy, Benjamin
Nieva, Jorge
Herman, James
Velculescu, Victor
Anagnostou, Valsamo
Baylin, Stephen
Brahmer, Julie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3ada9b6e9b3e49198ad9c4764bf98548
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ada9b6e9b3e49198ad9c4764bf98548
Other Identifiers
E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.0604
