Cryo-EM of prion strains from the same genotype of host identifies conformational determinants
Cryo-EM of prion strains from the same genotype of host identifies conformational determinants
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Prion strains in a given type of mammalian host are distinguished by differences in clinical presentation, neuropathological lesions, survival time, and characteristics of the infecting prion protein (PrP) assemblies. Near-atomic structures of prions from two host species with different PrP sequences have been determined but comparisons of distinct...
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Full title
Cryo-EM of prion strains from the same genotype of host identifies conformational determinants
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TN_cdi_doaj_primary_oai_doaj_org_article_3ba439d713654222b77cf5fa681300c3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ba439d713654222b77cf5fa681300c3
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1010947
