Sacubitril/valsartan mitigates cardiac remodeling, systolic dysfunction, and preserves mitochondrial...
Sacubitril/valsartan mitigates cardiac remodeling, systolic dysfunction, and preserves mitochondrial quality in a rat model of mitral regurgitation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Sacubitril/valsartan (SAC/VAL), an angiotensin receptor blocker-neprilysin inhibitor, has been widely used to treat several types of heart failure. Nevertheless, the effects of drugs in mitral regurgitation patients, from the molecular level to therapeutic effects, remain unclear. This study investigates the roles of SAC/VAL on cardiac function, mi...
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Sacubitril/valsartan mitigates cardiac remodeling, systolic dysfunction, and preserves mitochondrial quality in a rat model of mitral regurgitation
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TN_cdi_doaj_primary_oai_doaj_org_article_3c55cb85321c4ee9add81cdec8e279a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c55cb85321c4ee9add81cdec8e279a8
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-38694-6
